This session emphasizes the connection between pain recognition and low-stress handling in exotic species. Participants will develop skills in using validated tools like the Rabbit Grimace Scale, CANCRS, Bristol Pain Scale, and interpreting subtle behavioral changes in ferrets, rodents, and lagomorphs. The lecture will also explore evidence-based approaches to reduce fear and restraint-related stress in clinical settings, including handling techniques, environmental adjustments, and recovery room strategies. Attendees will leave with practical methods to improve patient welfare and increase diagnostic accuracy by minimizing stress.