During this lecture the audience will learn the practical and safe use of local anesthetics. Will include a “video wetlab” that demonstrates various techniques suitable for any clinician to master, with a focus on circumstances specific to the patient in any clinical setting Learning Objectives 1. Understand the rationale and industry guidelines for the use of local anesthetics 2. Understand the mechanism of action and differences/similarities between various local anesthetics 3. Learn potential adverse effects and safe use of local anesthetics 4. Understand the indications, safety/stability, and practical use (label and extra-label) of liposome-encapsulated bupivacaine (Nocita™)