Canine polyuria and polydipsia (PU/PD) often indicate underlying endocrine disease and require a structured diagnostic approach. This session reviews key clinical clues, minimum database findings, and appropriate use of screening and confirmatory tests for common endocrinopathies, including hyperadrenocorticism, hypoadrenocorticism, diabetes mellitus, pheochromocytoma, and hyperparathyroidism. Emphasis is placed on practical test selection, interpretation, and clinical decision-making to improve diagnostic accuracy in dogs with suspected endocrine-mediated PU/PD.

Learning objectives:

• Describe a stepwise diagnostic approach to endocrine-related PU/PD in dogs.
• Identify appropriate screening and confirmatory endocrine tests.
• Interpret diagnostic results to differentiate common endocrinopathies.