We will cover image acquisition for the 5-acoustic windows (views) of the AFAST exam and its target-organ approach to not only detect free fluid but also for obvious soft tissue abnormalities with clear advantages over physical exam, basic blood and urine testing, and radiography. Through the AFAST Approach and its 5 standardized views, the clinician sees their problem list and thus diagnostic and treatment plans are often more accurate and better streamlined. Applications are widespread and practical for all veterinarians including the general practitioner, the emergency veterinarian, and the clinical specialist. Practical everyday cases are used to show this approach’s clinical impact.