Disorders affecting glucose homeostasis in ferrets are extremely common. Human portable blood glucose meters tend to underestimate blood glucose in ferrets.1,2 The glucometers OneTouch Ultra 2 (LifeScan Inc) and Contour (Bayer) showed differences to actual glucose levels between +9.2 mg/dL to -53.2 mg/dL (OneTouch Ultra 2) and +36.0 mg/dL to -64.8 mg/dL (Contour) in 95% of the cases. The canine setting of the AlphaTrak (Zoetis), considered more accurate than the feline one, differed to glucose levels measured with a laboratory analyzer of +34.1 mg/dL to -30.3 mg/dL in 95% of the cases.2 A subsequent model of the same veterinary glucometer (AlphaTrak 2, Zoetis) showed similar inaccuracy, with results expected to differ between +38.5 mg/dL and -47.3 mg/dL.3 The objective of the present study is to evaluate the performance of a new model of a widely-distributed veterinary portable blood glucose meter in ferrets (AlphaTrak 3, Zoetis). Ferrets presented at a veterinary referral hospital and that had glucose measured with a hexokinase-based analyzer for clinical reason had, at the same time, glucose measured via two strips of the veterinary portable blood glucose meter. Bland-Altman analysis was used to determine agreement between the portable glucose meter and the reference analyzer. Preliminary results showed a mean difference of 2.8 mg/dL (18.2% of reference value), ranging from +65 to -31 mg/dL. The newer model of the veterinary portable blood glucose meter on a canine setting may be more accurate than previous models, but caution is warranted when interpreting results obtained with it. References (no space)