Nutritional and metabolic diseases remain prevalent in captive reptile populations. One of these diseases is gout- a condition in which urate crystals deposit into various organs/structures within the reptile’s body. Among the reptile groups that seem predisposed to this disease are the varanids, specifically the Australian dwarf monitors in the subgenera Odatria. This retrospective study investigated the genetics, husbandry, and clinical progression of gout in Odatria. Husbandry within the study population was in line with previously published husbandry guidelines for Odatria, and most of the varanids in the study population had articular gout. From this study population, unique presentations of gout- articular gout in the spine, spontaneous necrosis of the tail, and hereditary gout- have been described and recommendations for early detection of gout are provided. Looking at this data in tandem with varanid physiology, metabolism, and insect biology and nutrition, some recommendations are made to possibly prevent the development of gout in these lizards.