This presentation provides a practical, evidence-based review of anesthesia for rabbits and ferrets, equipping veterinary professionals with the knowledge and confidence to safely anesthetize these unique patients. Attendees will learn species-specific approaches to patient handling, pre-anesthetic assessment, venipuncture and catheter placement, sedation and analgesia protocols, induction and airway management, anesthetic monitoring, perioperative support, emergency interventions, and recovery. Emphasis is placed on recognizing the physiologic differences between rabbits and ferrets, avoiding common complications, and applying practical techniques that can be immediately incorporated into everyday clinical practice to improve patient safety and anesthetic outcomes.