A nine-year-old ball python (Python regius) presented to the emergency service following accidental ingestion of three HotHands® hand warmers that were being used to keep the patient warm during a power outage. HotHands® hand warmers are sachets containing iron powder, water, salt, activated charcoal, and vermiculite that produce an exothermic reaction when exposed to air. Per the manufacturer, the exothermic reaction can produce temperatures of 100°F to 180°F for a duration of 1-to-20+ hours, adding the concern for thermal damage to the possibility of obstruction and risk of sodium toxicity. Upon presentation, the snake was bright, alert, and responsive, with pain on mid-coelomic palpation. Radiographs showed three warmers in the area of the stomach. In-house plasma chemistry performed on intake (VetScan VS2) showed no abnormalities. The sachets were removed under anesthesia via flexible endoscopy with air insufflation, using a combination of grasping forceps and manual manipulation. Endoscopy showed gastric mucosal inflammation. The patient recovered well following anesthesia and was discharged after 24 hours in the hospital. The owner noted one neurologic episode 12 hours after leaving the hospital, where the pet thrashed and rolled for less than 20 seconds. Follow-up plasma chemistry one week later showed no abnormalities. Feeding was reintroduced at six weeks post procedure using carnivore critical care, and the patient has been doing well. This is an ongoing case and updates will be provided. The presentation is meant to share a cautionary tale of usage of these handwarmers during power outages and guidance for future cases.