A 2-year-old, neutered male ferret, with a history of ingesting a fragment of a plastic toy two months prior, was presented with intermittent vomiting of plastic fragments and acute abdominal pain. Over the preceding two months, the ferret also exhibited mild diarrhea and a diminished appetite, followed by severe abdominal discomfort. Radiographic imaging revealed gas accumulation in the stomach and proximal small intestine, while contrast studies indicated an obstruction at the proximal duodenum. Endoscopic evaluation was performed under general anesthesia using a 5.0 mm video-bronchoscope to explore the stomach and duodenum. The stomach contained significant fluid, which was evacuated via a feeding tube prior to endoscopic intervention. However, limitations in the bronchoscope’s lens clearance compromised visualization. Consequently, a concurrent laparotomy was performed to inspect the serosal surfaces of the stomach and duodenum. Two irregularly shaped plastic fragments were identified in the stomach, with one causing duodenal obstruction. The foreign body was successfully manipulated into an endoscopic stone extraction basket and removed without the need for gastrotomy or duodenotomy. The foreign body was safely retrieved using a combination of gastroscopy and laparotomy, obviating the need for internal organ incisions. This approach resulted in a more rapid recovery compared to traditional gastrotomy or duodenotomy due to reduced surgical trauma. In facilities lacking endoscopic equipment, a modified procedure utilizing a suction or stomach tube with endoscopic instruments may serve as a viable alternative to flexible endoscopy.