Rabbits are at a higher risk of anesthetic complications, including mortality, compared to dogs and cats. The largest study on peri-operative mortality showed a 24-hour mortality rate of 3.9% (7/178) for rabbits undergoing general anesthesia, with 42.8% (3/7) rabbits dying during induction. Historically, rabbit induction has been performed with anesthetic gasses and there are limited reports of the use of propofol in clinical practice. The objectives of our study were to compare the usage of propofol versus gas anesthetic in client-owned rabbits in terms of their mortality rate and peri-anesthetic complications. All the rabbits that had general anesthesia induced with propofol in a 4-year timeframe by the exotics service of a veterinary teaching hospital were included in this retrospective cohort study. A total of two hundred rabbits will be included. Rabbits were anesthetized for a variety of procedures, ranging from elective (eg ovariohysterectomy) to emergent procedures (eg gastrointestinal obstruction, liver lobectomy). The data collection will be completed in January 2025 and conclusions will be presented when the final version of the abstract is due.