Hepatic lobe torsion is a rare condition observed in rabbits, associated with gastrointestinal motility disorders. Clinical signs are nonspecific, but elevated hepatic enzymes are commonly detected in blood tests. While radiographs are typically nondiagnostic, Doppler ultrasound is useful, though it may be inconclusive in the early stages. Contrast-Enhanced Ultrasound (CEUS) is a more reliable method for diagnosing the absence of hepatic perfusion. Cases of hepatic lobe torsion have been diagnosed in rabbits presenting with depression and hypoactivity. Hematologic and biochemical tests revealed abnormalities in hepatic values, particularly elevated AST levels. FAST ultrasound showed peritoneal effusion and an abnormal hepatic lobe, which was confirmed by CEUS, demonstrating a lack of vascularization. Differential diagnoses included hepatic infarction and thrombosis. The diagnosis is performed in emergency care and during the night shifts by the emergency vet. The condition was surgically treated with hepatic lobe excision. Postoperative recovery was rapid and the rabbits regained appetite and fecal production. Follow-up exams showed stabilization of blood parameters. These case studies emphasize the effectiveness of combining ecoFAST and CEUS for the timely diagnosis of hepatic lobe torsion, a technique that is safe and effective even for operators with limited ultrasound experience. Further studies are needed to standardize the combined use of these techniques in veterinary practice.