The caudal vena cava to aorta (CVC:Ao) ratio has been measured in dogs to evaluate the hemodynamic status but has not been utilized in rabbits. The objectives of this study were to create a reference range for the CVC:Ao ratio on CT scans for systemically healthy rabbits and to determine if the CVC:Ao ratio is smaller in rabbits with various conditions and in different hemodynamic states. Diameters of caudal vena cavas and aortas were measured in the thorax and the abdomen of abdominal CT scans of rabbits presented at a veterinary teaching hospital. Thoracic and abdominal CVC:Ao ratios were measured in every scan by a veterinarian after a pilot with a board-certified radiologist. Unclear measurements were further evaluated by the board-certified radiologist. The CVC:Ao ratios ranged from 0.68 to 1.54 in the thorax and 0.63 to 2.28 in the abdomen. The median ratios were 1 in thorax and 1.19 in the abdomen. The ratios in the thorax and abdomen of volume depleted and hemodynamically stable were compared. CVC:Ao ratios were on average larger in the abdomen compared to the thorax. This ratio could be helpful as an objective way of assessing hemodynamic status in rabbits.