Have you ever struggled to decide whether cefazolin, ampicillin/sulbactam, or even enrofloxacin is the best choice for an emergency patient with a complex infection? If so, this lecture is tailored to help you make more informed decisions. In emergency settings, where time is critical and patient conditions vary widely, choosing the right empiric antibiotic can be challenging. This talk will dive into best practices for antibiotic prescribing in emergency cases, covering key presentations such as wounds, respiratory infections, and a variety of surgical patients. You’ll learn how to weigh factors like infection type, likely pathogens, and antibiotic susceptibility when making rapid decisions. Whether you're managing an infected wound or selecting antibiotics for a complex surgery, this lecture will provide practical strategies to optimize your antibiotic choices, while also adhering to antibiotic stewardship principles to minimize resistance and ensure the best patient outcomes.