Arterial blood pressure provides a sensitive assessment of a patient’s health status under anesthesia. Normal ranges for arterial blood pressure have not been established in bearded dragons due to difficulty of arterial catheterization. A 4-year-old female bearded dragon with a history of abnormal follicle development had a bilateral ovariectomy performed at a veterinary teaching hospital. The patient was pre-medicated with ketamine (10 mg/kg), dexmedetomidine (0.03 mg/kg), midazolam (0.75mg/kg), hydromorphone (0.5 mg/kg) intramuscularly and a doppler was secured on her ventral thorax to obtain her heart rate throughout the procedure. The patient was intubated with a 2.0 mm cole endotracheal tube. A 24 gauge arterial catheter was accidentally placed into the ventral tail artery when attempting catheterization of the ventral tail vein. On initial placement, the blood in the catheter was observed pulsing. Blood gas measurements confirmed arterial blood. The arterial catheter was used for continuous blood pressure monitoring during surgery and recovery. The pre-surgical arterial blood pressure was 37/35 (35), the surgical blood pressure was 35/31 (32), the blood pressure at extubation was 37/34 (35), and the blood pressure upon recovery, 3 hours from the start of surgery, was 41/37 (38). The procedure was uneventful, and the bearded dragon was healthy upon recheck. Based on a literature search, this is the first time that arterial measurements are obtained in a pet bearded dragon under anesthesia. Veterinarians should be aware of the potential risk of cannulating the ventral teil artery and can use these values as a preliminary reference.