Three macropods (red kangaroo, Osphranter rufus, n = 2; Bennett’s wallaby, Notamacropus rufogriseus, n = 1) were presented to referral hospitals for traumatic coxofemoral luxation. Both red kangaroos were client-owned and tolerant of handling, however, the Bennett’s wallaby was zoo-housed and intractable. Coxofemoral luxation was diagnosed radiographically and closed reduction was unsuccessful in all cases. A toggle pin fixation was elected over femoral head ostectomy to preserve joint anatomy. Anesthesia was induced, and lumbosacral subarachnoid (spinal) analgesia was performed in one kangaroo. Anti-inflammatory, analgesic, and antibiotic therapies were instituted in all cases peri- and post-operatively. A craniolateral surgical approach was made over the coxofemoral joint. Open reduction was performed and a toggle pin (Tightrope® system) was placed. An additional iliofemoral suture technique was performed in one kangaroo. Post-operative radiographs confirmed improved joint reduction and appropriate implant position. One kangaroo presented post-operative subcutaneous edema of the distal ipsilateral limb, which resolved with supportive therapies. Initial post-operative management was unremarkable in the wallaby and second kangaroo. Exercise restriction was instituted for 6-8 weeks before gradually increasing activity. The wallaby re-presented 4 months later for a right subtrochanteric femoral fracture. On radiographic and intra-operative evaluation, there was no apparent association between this fracture and the previous luxation repair. Although management is ongoing in one case, no clinical or radiographic evidence of implant failure has been appreciated in the remaining two cases over 12 months post-operatively. Therefore, toggle pin fixation should be considered for coxofemoral luxation in macropods to preserve joint anatomy and function.