North American beavers (Castor canadensis) are semi-aquatic mammals that are highly social. These herbivores reside along the banks of freshwater habitats such as rivers, streams, and ponds. Their physical adaptations such as a broad, flat scaled tail, compact body, large, webbed hind limbs, and thick dense waterproof coat contribute to their ability to live in aquatic environments. Most published literature about the species originates from field research and wildlife rehabilitation. Beavers primarily have crepuscular and nocturnal behaviors. Therefore, it is difficult for researchers to make substantial observations of beavers in their natural environments. It is uncommon for beavers to be kept under managed care. The lack of references attributed to the unique lifestyle of beavers provides little guidance for zoological facilities housing beavers. Beavers are the largest rodent species in North America, but they have similar challenges to small rodent species in a clinical setting. Examples of these challenges include sensitive gastrointestinal system, poor visualization of the glottis during intubation, and malocclusion. Three, juvenile, male orphaned beavers deemed unfit for release from rehabilitation, recently became resident animals at Mississippi Aquarium. All three individuals presented with ocular conditions that required multiple anesthetic exams throughout the year. This lecture will focus on the veterinary technician’s role in routine medical care for North American beavers. Topics summarized will include health assessments, venipuncture, diagnostic imaging, anesthesia, nutrition, and welfare.